Sustainability assessment of the food supply chain and its members is instrumental in achieving a sustainable food future. Despite being influential members of the food supply chain, no comparison of sustainability frameworks from the supply chain perspective of food manufacturers has been conducted so far. This research investigates the suitability of seven sustainability frameworks for food manufacturing companies by evaluating their connectivity to the up- and downstream food supply chain as well as their food sector specificity. The findings show that none of the frameworks fulfils both food sector specificity and full integration into the up- and downstream supply chain, calling for further research on more harmonized and integrated sustainability assessment throughout the food supply chain.