This paper presents a summary of a study of Federal programs supporting multicounty substate regional activities. The study identified 39 Federal programs supporting substate regionalism that were operating during the 1977-79 period. The programs were identified on the basis of five criteria: (1) Federal connection with regional activities, (2) multicounty area focus, (3) planning and policy development focus, (4) local control, and (5) a continuing nature. The paper presents an overview of the study, identifies the 39 programs, and discusses their key features. Detailed analysis of the programs is available in other reports.