The main aim of this paper is to describe the SWOT elements of cotton cultivation in Greece. For this purpose, research conducted combining focus groups and Delphi methodologies for the general areas of Thessaly, Macedonia, Thrace and Central Greece, from April to May 2018. According the results “fame of the product”, “method of collection”, “coupled aid”, “size of cultivation” and “delivery” belong to the contributing factors of cotton. On the other hand, “taxation”, “bureaucracy”, “high land rents”, “rising oil prices”, “low growers’ price” and “scattered land holdings” affect negatively the cotton cultivation.