This article aims to determine the main factors related to technology and labor nutrition that influence the management of organizations in transmodernity, in order to orient them towards the quality of life and sustainability. Transmodernity is used as a category of philosophical origin, comparable to other conceptions that seek to demarcate paradigmatic cycles in human history and that are strongly marked by digital-based technology. For its part, quality of life and sustainability are used as categories that encompass medical-biological aspects of the human being, as well as behavioral elements whose manifestation translates into a life considered healthy and, therefore, labor-productive. Hence, nutrition is considered as a whole (that is, involving food production and consumption, physical activity, and elimination of toxic substances), as well as its relationship with technological advances in pursuit of decent work, as a fundamental element of sustainable development and its influence on food security. The research was developed under a fundamentally documentary and hermeneutic methodology. The central guidelines are based on Gadamerian (and in some points, Derridian) postulates, which allowed visualizing both historical aspects of the terms, as well as the current conceptions of the categories, also allowing epistemological disruptions when necessary. The methodological position ends in a conceptual reconstruction, through a contrast with statistics, concepts, and current premises, published by international organizations working on the different relational topics. As a general conclusion of the research, it can be stated that nutrition management is necessary for today's organizations in the different departments and organizational aspects. Here the technology of the so-called industry 4.0 has a fundamental role (for example, through nanotechnology, nutritional genomics, food computing, among others), to make it more precise and practical. Thus, a nutrition management 4.0 can drive the improvement of the quality of life of the working human being.