Tobacco production in Croatia is predominantly carried out on family farms. The same applies to drying, preparation and packing for sale. The aim of this paper was to determine the economic efficiency of tobacco production at family farm Dumančić from Kutjevo for the period 2012-2016. Based on the collected data of technological and economic factors of production, calculations were made as a basis for defining production performance indicators. The highest profit was realized in 2013 in the amount of 14.876,64 HRK per hectare. Incentive was determined as the most significant item in the structure revenue and cost of labor in the structure. In the case of the analyzed family farm the values of economic indicators of productivity, economy and profitability point to an economically efficient production of tobacco.