The aqueous extract of pineapple leaves and patent anthelmintics albendazole (BenazolO) and ivermectin (Vermic0) were assessed against acaridae in indigenous chicken. Among these, extract of Pineapple leaves was administered @ of 1 gm/kg body weight for seven consecutive days while albendazole @ full 50 mg/kg body weight for 3 days, and ivermectin @ 0.2 mg/kg body weight s/c given as a single dose. Results showed that pineapple leaves extract caused gradual increase of 100 % efficacy up to day 28th of treatment. Haematological analysis revealed that the aqueous extract of Pineapple leaves did not show any adverse effect on blood parameter in treated birds. But Benazol® and Vermic® were effective. Pineapple leaves is considering more suitable one it should be given conclusion that pineapple leaves were effective against ascariasis in chicken.