Effects of the crude ethanolic extract of RueIlia tuberosa on analgesia in mice

The analgesic effects of organic extracts of Rue/la tuberosa using animal model like mice were studied. Four groups of mice (n=7) were taken in this study and test samples (250 mg/kg & 500 mg/kg), control (tween+water) and diclofenac-Na (25 mg/kg) were given orally by means of a feeding needle. A thirty minutes interval was given to ensure proper absorption of the administered substances. Then the writhing inducing chemical, acetic acid solution (3%) was administered intra peritonially to each of the animal of four groups. After an interval of fifteen minutes, which wos given for absorption of squirms (writhing) was counted for first 20 minutes. Ethanolic extract of RueIlia tuberosa has demonstrated significant reduction of writhing both at higher dose (500 mg/kg) and lower dose (250 mg/kg) comparative to that of a standard analgesic diclofenac- Na. Thus the crude ethanolic extract of Rueffia tuberosa has moderate antinociceptive effect comparative to that of a standard analgesic Diclofenac- Na.


Issue Date:
2006-12
Publication Type:
Journal Article
DOI and Other Identifiers:
Record Identifier:
https://ageconsearch.umn.edu/record/276558
ISSN:
2408-8684
Language:
English
Published in:
Journal of the Bangladesh Agricultural University, 04, 2
Page range:
293-298




 Record created 2018-09-21, last modified 2020-10-28

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