An experiment was conducted to study the effect of feeding Meat and Bone Meal (MBM) on total amino acid (TA) and digestible amino acid (DA) basis on the performance of 150 straight run "Vencobb" broiler chicks. Maize, soybean and fishmeal based control diet, Ti (without MBM) and other four diets, T2 (5% MBM on TA), T3 (5% MBM on DA), T4 (10% MBM on TA) and T5 (10% MBM on DA) were formulated and supplied to 5 groups of birds. The body weight of broiler at 42 days were 1663.33, 1563.33, 1705, 1499 and 1730 g for Ti, T2, T3, T4 and T5 respectively. The body weight was significantly improved at 5'h& 6'h week of age in T3 and T5 compared to other treatments. During 2-6 weeks feed conversion ratios were 1.95, 2.09, 1.86, 2.20 and 1.83; protein efficiencies were 2.51, 2.33, 2.58, 2.20 and 2.60; energy efficiencies were 16.70, 15.53, 17.43, 14.80 and 18.07 for the treatments Ti, T2, T3, T4 and T5 respectively. Feed conversion ratio was significantly improved in T3 compared to T2 and in T5 compared to T4.Dressing Yield was also better in. T3 and T5 and higher in male than female. Feed cost was higher in control diet while, feed cost/kg live weight was lower in T3 and T5 and profit was also higher in diets formulated on digestible amino acid basis. It may be concluded that up to 10% MBM can be included in broiler diets on DA basis for better performance and maximum profit.