The paper intends to make an analysis at regional level in the South-East region of the country in order to determine the present situation of agriculture in this region compared to the whole country. The paper investigates the crop structure, the irrigated area and the number of irrigation equipment in the region, the market orientation of farms, the type and development level of the non-agricultural activities, the labour force, and the specialization of farms. The objective of this paper is to analyze the regional agricultural characteristics and to determine the level of entrepreneurship in the area, so that farmers and regional policies might better interfere in order to help farmers adjust their production to the market and obtain a benefit. A comparison with the situation at the whole country will be also provided. The paper concludes that Romanian subsistence agriculture is still a “modus vivendi”, and most likely only time and the force of new technologies employed by the large commercial companies will partly solve the issue.