Keratoconjunctivitis Sicca in canines is one of the most underdiagnosed pathologies, mainly in countries like Nicaragua, where veterinary clinical practice is still incipient, the objective of this study was to determine the frequency of Keratoconjunctivitis Sicca, applying the Schirmer test in 28 dogs of various breeds, studied during canine deworming campaign in a neighborhood of the city of Managua. There were 7/28 positive cases for unilateral Keratoconjunctivitis Sicca (25%, CI 95%: 7.17-4.82), the Creole dog’s breed was the one that presented the highest frequency of cases with 4/10, in the Pitbull and Chow Chow breeds, 2/7 and 1/2 were positive respectively, in Doberman, French Poodle, Siberian Husky, Labrador, German Shepherd and Pekingese breeds no cases were found. Sex was not a predisposing factor, since the frequency of positives in females was 2/13 and in males 5/15 (p≥0.05). The mean tear film in young dogs was 18.4 mm and in adults, it was 21.0 mm, showing a significant difference (p=0.049). This study highlights the need to include canine ophthalmological check-up in the daily clinical review, applying complementary tests for the early detection of Keratoconjunctivitis Sicca.