Chinese giant salamander (Andrias davidianus) is salamander germplasm resource that only distributed in China. It is the material basis of the evolution principle research, genetic research and artificial breeding. Since the 1990s, overharvesting, water pollution and habitat changes have seriously destroyed the germplasm resources of A. davidianus, their population density has decreased since then. Strengthening the protection and rational utilization of A. davidianus germplasm resources are key factors in impacting the healthy, stable and sustainable development of A. davidianus industry. Under the above background, we discussed the current problems with the protection for A. davidianus germplasm resources, put forward suggestions for the conservation of A. davidianus germplasm resources. It is expected to provide a reference to effective protection for A. davidianus germplasm resources, and provide a scientific foundation for further studies, so as to promote the high-quality development of related industry.