The Programme de Microfinance Rural (PMR) was implemented in the rural, impoverished regions of Koulikoro, Kayes, Ségou, Sikasso and Mopti in Mali with support from the International Fund for Agricultural Development (IFAD). This paper shares the results of a qualitative study designed to improve understanding of the programme’s delivery and explore its impacts in terms of collective agency and efficacy, as well as the use of resources in households, with attention paid to the role of gender in addressing these issues. The findings suggest that the PMR actively engaged women and expanded access to loans through community-based credit groups. It also overcame negative community experiences with previous microfinance programmes to maintain a positive local reputation. In many cases, the PMR led to significant economic benefits for women but, in other cases, loan repayment terms posed a challenge. The collective agency of PMR credit groups built upon progress made by similar community groups in existence prior to the arrival of the PMR. The resources provided by the PMR strengthened these groups and helped enable them to expand their collective efficacy and ability to benefit the community more broadly. Women were most often the target loan recipients and frequently had a strong voice in the PMR groups, which were influential in the community. There is little evidence, however, that the PMR activities and credit group participation spilled over to strengthen either women’s political power in the community or their influence and empowerment in their own households. The paper concludes with specific recommendations for strengthening future iterations of the PMR or similar programmes.