Excerpts: Crops grown in the Midwest range from alfalfa to wheat, and from sweet corn and specialty crops to perennial crops. Each has its own sensitivity to weather within a growing season; however, the most sensitive stages are crop establishment and harvesting. The Midwest produces a large number of pigs, turkeys, dairy, beef, broilers, and layers. These livestock systems are also sensitive to the weather variations during the year and, in particular, hot weather during the summer. Forests cover a large expanse of the Midwest ranging from boreal forests around the northern Great Lakes to oak-hickory forests of the Ozarks. The Midwest is characterized by savannas and open woodlands, which mark a major transition zone between forest and grassland biomes within the U.S. Variations in weather and ultimately climate affect all agricultural and forest systems. They include temperature extremes, excess or deficit precipitation, severe storms, and wind. The Midwest Regional Climate Hub is working across a range of crops, forests, and livestock production systems to assemble the available information into tools and practices that can increase the resilience of these systems to climate change.