We quantify the impacts of a potential Investment Facilitation Agreement (IFA). The analysis is based on an innovative multi-region general equilibrium simulation model. The model extends the basic GTAPinGAMS structure. The model is calibrated to GTAP 10 (early-release) data characterizing bilateral trade and the social accounts. Consideration is given to Foreign Direct Investment (FDI) and monopolistic competition. The model shows empirically relevant gains associated with removal of investment barriers. Key drivers of the gains are identified in sensitivity analysis. We contribute to the relatively scarce research on investment facilitation and provide policymakers with information on potential effects of a IFA.