Mega farms have the potential to transform Malawian agriculture. While the establishment of new mega-farms is supported, strengthening existing large farms by enhancing their human resource capacity, promoting sustainable agricultural practices, and addressing other issues that limit productivity will generate quick wins. It is also important for Government to put in place deliberate policies that will promote meaningful interaction between mega-farms and surrounding smallholder farmers and communities. The management and governance of the mega-farms should be private sector-led, with Government providing supporting infrastructure and conducive marketing and trade policies. Furthermore, the choice of the focus crops or livestock on the mega-farms should be consistent with suitable climatic, soil, and other ecological factors.