The COVID-19 epidemic has caused the closure of French higher education institutions leading to a series of lockdowns that have affected the mental health of students. We use the POMS (Profile of Mood States) questionnaire developed by McNair et al. (1971) to identify the state of the mental health of students in a French Management School (post-high school level, aged 18+). Our results show that a significant proportion of students show altered mental states and generalized fatigue. 41% of the 1,123 respondents had a worrying mental health condition. We highlight the impact of the absence of social ties and of physical and sports activities. Finally, we suggest that techniques to reduce states such as stress and anxiety be introduced into the curriculum.