This theme issue of Choices, commissioned by the Council on Food, Agriculture and Resource Economics (C-FARE), in collaboration with the Northeast Regional Center for Rural Development on behalf of the Regional Rural Development Centers (RRDCs), includes eight papers that examine impacts of the pandemic and effects of selected federal policies designed to mitigate adverse impacts. Topics include: employment and job loss trends, impacts on agriculture, and impacts on other sectors of the economy, including tourism, childcare, banking, broadband, and healthcare facilities.