Texas High Plains producers faced many new uncertainties with the arrival of COVID-19. Significant supply chain disruptions, reductions in consumer demand and decreases in travel negatively affected agricultural operations. In addition, efforts taken to stem contagion lessened the amount of food consumed away from home, and restrictions on movement sharply reduced gasoline usage, and with it demand for grain ethanol. Elevated cases among livestock processing facilities disrupted normal business practices and increased costs. In fact, early in the pandemic the Texas High Plains region was considered a COVID-19 “hot spot” as many area processing plants faced reduced workforces and slower production times due to high numbers of positive cases. This study looks at the farm-level impacts of COVID-19 on six case study model operations created by local Texas A&M AgriLife Extension Risk Management Specialists.