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Abstract
National agricultural research systems in many developing countries are evolving programs that use biotechnology to address constraints on productivity and to meet pressing agricultural needs. These programs challenge research managers and decision makers to identify relevant end users, develop national expertise, priorities, and policies for biotechnology, and to secure financial resources for implementation. This report describes a four-phase framework for decision making to assist directors of national agricultural programs and financial ministries in establishing priorities and policies for national biotechnology initiatives, determining design and implementation objectives, and considering avenues available for technology transfer. The decision-making process stimulates interaction among national, managerial, and research leaders to develop and advance a strategic approach for biotechnology activities that have often arisen independent of one another.