The U.S. beekeeping industry may experience annual losses of $26 million to $58 million if the Africanized honey bee (AHB) colonizes the South and Southwest and causes the kinds of problems it has caused elsewhere. If the AHB colonizes the area that has at least 240 frost-free days a year, losses could range from $49 million to $58 million annually, depending on the behavior of the bee. If the AHB colonizes the area south of latitude 32° North, the economic losses could range from $26 million to $31 million annually, depending on the behavior of the AHB. Every aspect of beekeeping—honey and beeswax production, queen and package bee production, pollination, and migratory beekeeping—could be adversely affected.