Biogas fertilizer is widely used in agricultural production, and it can be used in a variety of ways, including liquid spraying, root fertilization, presoaking and biological pesticides, etc. It can improve soil structure, increase the content of soil organic matter and available nutrients, and increase crop yield. In addition, there are some problems in the utilization of biogas fertilizer. Some details that need to be paid attention to and can not be ignored should be further studied and discussed to achieve a final principle of harmonious, safe and efficient use, so as to ensure the benefit maximization of biogas fertilizer as an economic fertilizer source. Therefore, this paper summarizes the main ways and methods, existing problems and corresponding development measures concerning the application of biogas fertilizer in agriculture, in order to provide some reference for the utilization of biogas fertilizer in the field of agriculture and make it universal, safe and stable.