Cameroon poultry production is still dominated by individual farmers who account for about 70% of the production distributed throughout the national territory. What is the margin relationship between actors? The study estimates the margin size by actor on the nodes of the poultry-meat supply chain, specifying node relationships. Primary data was made use of with questionnaires as the main research instrument. An elaboration of margin, mark-up and cost analysis were used. Findings reveal significant margin differences between producers, wholesalers and retailers. There is also need to encourage the survival of the subsector, dominated by females whose economic security has been advocated.