Purpose. Based on the econometric model (Kuznets curve) of the relationship between economic growth and environmental pollution – Environmental Kuznets Curve, this article analyses the relationship between economic growth and environmental pollution in Henan Province, and studies the natural economic relationship. Methodology / approach. Three kinds of regional pollution index data of waste gas pollution and solid waste pollution and relative data of per capita GDP in Henan province were analyzed by using STATA software and OLS method was used to fit the relationship between environmental quality and economic growth, and the regression curve with the best fitting degree was obtained. Results. This article analyses the relationship between the overall environmental quality and economic growth in Henan Province over the years. According to the established data model it is obviously that economic growth itself cannot promote the improvement of environmental quality. To realize the double goals of economic growth and environmental protection, the key is to find out the inherent law of economic change in the process of economic growth, so as to construct a long-term mechanism of promoting environmental friendly economic growth. It is necessary: strengthening of pollution control and reduce pollutant discharge; follow the economic road of recycling resources; optimizing industrial structure and promoting coordinated sustainable development; adhere to the policy of energy saving and emission reduction. Originality / scientific novelty. Author’s developed econometric model is very useful in empirical assessment for the sustainable development of resources, environment and economy in Henan Province, and to provide a decision-making reference for the development of ecological environment in Henan Province. Accordingly, the proposed method, in the face of high-speed economic development today, put forward the countermeasures of economic sustainable development. Practical value / implications. Using the author’s proposed method leads to the achievement of the following results: can better promote Henan Province economy and ecological environment coordinated development.