The essence of personalized education is an innovative education that respects individual differences. With the continuous evolution of the times, the ability of innovation and entrepreneurship has become the key to reflecting comprehensive national strength. In response to the call of China to build an "innovative country", colleges and universities should cultivate students' individualized thinking and methods and abilities to solve problems on the basis of respecting the creativity and subjectivity of college students, and lay a solid foundation for students' future innovation and entrepreneurship. In this paper, the present situation of students' independent development promoted by personalized education at home and abroad was analyzed firstly, and the existing problems and solutions were pointed out. The study aims to contribute to the acceleration of China's innovation-driven development.