Agricultural exempt truckers continue to be a growing part of the national transportation system. But, the regulatory and economic environment surrounding these truckers has undergone significant changes. This paper analyses, based on a national survey of agricultural motor carriers, both the problems facing truckers as well as operating characteristics in relation to regional location. A Chi-Square test was used to test independence between region and the other variables of age, size, commodity hauled, and percent empty mileage. It was found that regionality has a strong impact on trucker problems and operating characteristics. It appeared that commodity specialization, which is closely associated to region, might be a determinant of many problems and operating characteristics experienced by these truckers. The study results indicated that studies by n-:searchers, and policies by policy makers based on aggregation of the national trucking industry should be instituted with some reservations.