The effects of bagging at different times in Mengyin area on the fruit quality and disease and pest incidence of Huimin short-cut Fuji apple were investigated, with unbagged fruit as the control. The results showed that among the apples bagged on May 5, May 15, May 25, June 2 and June 12, the single fruit weight and fruit shape index of the apples bagged on June 2 were highest, 308.1 g and 0.868, respectively; the peeled harness of the apples bagged during May 5-25 was higher than that of the control; the peeled harness of the apples bagged on June 2 and June 12 was lower than that of the control; the soluble solids content of bagged fruit was lower than that of unbagged ones, and no significant differences were found among different treatments; the coloring index of the apples bagged on June 2 was up to 100%; the smooth finish index of the apples bagged on May 5 reached 96.67%, the highest; the red chromatic value (a*) of bagged fruit was higher than that of unbagged ones, and there were no significant differences among different bagging treatments. The earlier the bagging was, the higher the incidence of black spot and bitter pit was. The incidence of black spot and bitter pit in bagged fruit was higher than that in unbagged ones. In conclusion, in Mengyin area of Shandong Province, bagging is better to be carried out on June 2, 45 d after the full bloom.