The agricultural sector, particularly the rice sector, is radically changing in India and the rest of the world. Rice remains the world’s most important food commodity, particularly in Asia, but it faces challenges such as climate change, degradation of farming areas, decreased water availability, and increased population. It is therefore appropriate to discuss these pressing concerns as the demand for rice is increasing sharply despite dwindling resources. This reality was examined at the 6th International Symposium on Hybrid Rice with the theme “Public-Private Partnership for Hybrid Rice.” The topics covered hybrid rice development, hybrid rice seed production, applications of molecular technology, crop and resource management, and the economics of hybrid rice. The symposium was held in Hyderabad, Andhra Pradesh, India, on 10-12 September 2012. It was hosted by the Indian Council for Agricultural Research (ICAR) and jointly organized by the International Rice Research Institute (IRRI) and the Directorate of Rice Research (DRR). A total of 440 representatives from the public and private sector of 32 countries participated.