An objective interpersonal comparison of wellbeing requires that people’s capabilities are considered. This paper operationalizes Sen’s capability concept in maize-based farming systems and assess how it influences farmers’ participation in the Planting for Food and Jobs programme in the Bunkpurugu-Yunyoo District of the Northern region, Ghana. We used data from 314 households through multi-stage sampling procedure. Capability was quantified using factor analysis, while its determinants were identified through multiple linear regression analysis. Afterwards, an instrumental variable probit model was used to examine the effect of capability on programme participation. The factor analysis results reveal two attributes of capability, which were labeled as human capability and institutional capability. These capability attributes are significantly enhanced by availability of markets and good roads. The probit model results provide substantial evidence that both attributes of capability influence farmers’ participation in the Planting for Food and Jobs programme. Specifically, a one standardized unit increase in institutional capability increases the probability of participation by 10.45%. The findings indicate that, for effective participation in agricultural interventions, farmers’ capabilities need to be enhanced. This could be achieved through the provision of, and/or improvement in infrastructure, including roads and markets in remote production centers.