Vegetation cover has acted as a source of carbon sinks and air purifier for a long period of time especially in developed cities thereby affecting the global climate change. The study was conducted to spatially estimate the Normalized Difference Vegetative Index (NDVI) which is a vegetation indicator for a period of 28 epoch years for Abuja from 1987 to 2014. The positive signatures of NDVI decrease from 2009 to 2014. Statistical analysis of the observed data samples at 95% confidence interval revealed that the changes observed in Year 2009 contributed most to the changes that was occurred in Year 2014.The modeled NDVI values for the year 2014 based on the regression analysis of the previous three years shows a significant agreement between the simulated values for year 2014 and the observed values. In general, there has been fast transformation of the vegetation cover to other land uses. The study reveals vegetation cover had reduced more significantly. It is also worthy to know that the model generated in this research can be used to predict future changes and trends in the vegetation cover. This will provide policy makers with useful information for the proper planning and design of the city and other capital cities over West Africa.