The purpose of this study was assessment of institutionalizing level of entrepreneurship in citrus processing and complementary industries in Khouzestan Province, Iran. The method of research was descriptive. The statistical population comprised managers of complementary and processing industry of citrus products in Khouzestan Province (N=75). For the purpose of this study, a census was conducted and opinions of all managers were studied. The main instrument in this study was a questionnaire the validity of which was established by a panel of experts and its reliability coefficient was obtained by using a Cronbach’s alpha (0.89). Institutionalizing level of entrepreneurship was assessed by three subsections that include: continuity, comprehensiveness and becoming a social reality. Based on the results, the level of continuity, comprehensiveness, and becoming a social reality, respectively, was low (2.4-2.6), moderate (2.83- 2.85), and moderate (2.71-2.84). Based on the results, the correlation between participation in extension programs, accountability, risk taking, tendency to be creative, competitiveness, attitude to entrepreneurship, the level of education and entrepreneurship institutionalizing was significant. In addition, multivariate regression analysis showed that the variables of participation in extension programs, accountability, risk taking, tendency to be creative, competitiveness, attitude to entrepreneurship, and the level of education had explained 63.6 percent (R 2 =0.636) of entrepreneurship institutionalizing’ changes.