In the last fifteen years, world tourism, considering the interest of users, included wine segment in the offer, which proved to be very successful. Wine tourism is present in world’s most famous viticulture regions in Italy, France, Germany, Austria... Wine tourism is very lucrative business in Europe. Most countries in our region have managed to fully resolve, stimulate and organize the so-called “wine tourism” by making “wine routes” in their own area like Wine roads in Slovenia and Croatia, Germany and Austria etc. Wine route is a special form of selling wine, catering, tourism and agricultural products of a vineyard area. It consists of natural beauties, the specifics of the environment through which the road leads, cultural and historical heritage, tradition and special quality of vineyard area. Republic of Serbia has many things to offer to foreign and domestic visitors, but first of all certain standards has to be meet for this type of tourism as it is practiced in wine developed countries of Europe. Opening of “wine routes” or “wine roads” is an effective form of stimulation for wine producers.