This study examines the economic potential of harvesting cellulosic biomass from corn and three types of sorghum rotated with soybeans using enterprise budgets constructed with experiment field data. The results show that harvesting of crop residue from grain sorghum, corn, and biomass from an energy sorghum that does not produce grain is economically feasible. Net returns from corn that produced grain and corn stover has the highest net return per acre. Dual purpose sorghum which produces sorghum grain and sorghum stover has the second highest net return per acre. Net returns from the other two sorghums were substantially less.