The paper aims at empirical evaluation of the impact of R&D expenditures on the bioeconomy innovativeness. The research is based on the cross-sectional analyses of correlation and regression between the value of biotech R&D expenditures and the number of biotech patents granted in the EU countries. In particular, the study attempts to assess a relative effectiveness of R&D expenditures in public and business sectors. The data for the analysis were extracted from the OECD Statistical Database and Eurostat Database covering the period 2009-2014. Given the availability of data the examined sample covers 11 countries. The results indicate a positive and statistically significant impact of biotech R&D expenditures on bioeconomy innovativeness in the pooled sample of countries and suggest a higher effectiveness of private sources of funding.