The aim of the discussion in this paper was to identify the components of the level of socio-economic development responsible for enterprises development in rural areas. In the first stage, was performed spatial autocorrelation analysis variations in the rate of enterprises and identified 4 municipalities groups: forming clusters of high values, clusters of low value, as well as cases of atypical occurrence in the high single or low values of the indicator. For each of the groups correlation analysis was conducted separately with respect to the components of the level of socio-economic development. Analysis of correlation coefficient in the designated spatial regimes revealed variable strength of a constituent of socio-economic change in the intensity of enterprises. In general for rural areas as important determinants were considered: the degree of labor market sustainability and prosperity and cohesion of the local community. The relatively high values of the correlation coefficient for all the analyzed components of the level of socio-economic development was observed only in the group of municipalities included in the clusters of high values (HH), which is adjacent communes with above-average growth enterprises.