Farmers need access to certified seed stocks for efficient production of traditional African vegetable seed. However, access to quality certified seed is constrained by several factors. Primary data from four selected regions of Tanzania was analyzed to examine the causal linkages among traditional African vegetable farmers’ decisions to participate in farmer-led seed enterprises and their access to quality certified seeds. The effect of farmers’ access to certified traditional African vegetable seed on revenue generated from their seed sales in the study locale was assessed. This study concludes that farmers’ revenue from traditional vegetable seed sales is positively and significantly influenced by access to certified seed. Indeed, access to certified seed can be increased, if farmers participate in farmer-led seed enterprises, and if they have more frequent contact with village extensionists. Relevant policy actions and recommendations for improving farmer-led seed enterprises are offered.