The development of the agricultural sector and the improvement of the food security situation are seen as essential components to sustainable development in Sub-Sahara Africa. However, continuing population growth, impacts of climate change and environmental degradation add to an unprecedented combination of pressures that threaten existing efforts and solutions. This article discusses the relation between the challenges of making agriculture more sustainable and meeting food security needs. Several solutions proposals are discussed and organic farming as one of them is used to develop decision criteria. Due to its involvement of all three dimensions of sustainable development, economic, social and environmental organic farming could be one possible approach to create a more sustainable agricultural system.