Yield gap survey (YGS) was carried out in nine selected communities in the Sudanno-Guinea Savannah (SGS) rice growing ecologies of Ghana in the 2012 and 2013 cropping seasons. One lead farmer was selected from each community to host researcher-managed fields. The specific objectives of the study were to determine the causes of yield gaps in rain fed and irrigated ecologies of the SGS of Ghana and to suggest ways by which the gaps can be bridged to enhance the production of the crop in Ghana In both 2012 and 2013 seasons, farmers in the Sudan savannah zone recorded higher gaps in rice yields (average 55%) than their compatriots in the Guinea Savannah (average 49%). The analysis of data collected from YGS indicated that factors such as difficult weather and soil conditions, insufficient access to mechanization services/improper land preparation, lack of fertilizers, the use of unimproved rice seed, untimely field operations and inadequate water and pest (in particular weed) management, were some of the key factors that adversely influence rice yields in the study area. Unrestricted access to mechanization services delivery, intensified use of improved rice seed, appropriate melioration with organic and inorganic fertilizers, together with robust soil and water management interventions are essential requirements for bridging experiment-based yield gaps for enhanced rice yields in the Sudanno-Guinea Savannah zones of Ghana.