After independence, Central Asian countries embarked on the path of radical socio-economic and political transformation. Growing economic openness of countries contributes towards joining the world community. Each of them in its own way has built a strategy of reforming the economy and solve the problems of the former administrative system. Today, Central Asian countries differ significantly in population, territory, natural resources, level of socio-economic development, political orientation. They are characterized by different degrees of readiness to cooperate and integrate with the rest of the world. The growing economic openness of the country contributes to refocus its entry into the world community. In the article on example of Uzbekistan discussed issues of foreign trade liberalization and mechanisms to reduce trade barriers, as factors for integration of countries in the region.