The aim of the study is to review the agricultural sector of Uzbekistan with the purpose of identifying the major constraints of development of the sector with special emphasis on fruit and vegetable subsectors, thereby to suggest policy recommendations for the development of the sector. Fruits and vegetables market and its supply chain potential has been studied in case of Samarkand region. Although analysis of recent reforms has provided opportunities for liberalization and modernization of agricultural production and marketing system in Uzbekistan especially for fruit and vegetable subsector, there is still a precondition for sustainable development of subsector. Hence policy suggestions are still in their implementation stage. Specific recommendations were also outlined pertaining to the key constraints identified; namely, pertaining to agricultural production and productivity, quality of land resources, irrigation, reforms, R&D, and agricultural marketing.