This study examines the relationship between adoption of NERICA varieties and the Total Factor Productivity among men and women. Data were collected from 342 rice farmers randomly selected in the central and northwest Benin. Total Factor Productivity was estimated using a Cobb-Douglass production function. The impact was estimated using the Local Average Treatment Effect. Results show that the adoption of NERICA variety improves Total Factor Productivity of potential adopters and it benefits men and women differently. Potential women adopters got a higher gain on their Total Factor Productivity than men. This finding suggests that targeting women with NERICA increase significantly rice productivity more than the case where men are targeted.