The routine monitoring of livestock and poultry products is the monitoring work carried out by the Ministry of Agriculture in order to grasp the quality and safety of national livestock and poultry products, and the sampling work is the first part of routine monitoring. This paper analyzes various factors during the implementation of sampling work such as preparatory work, sampling tools, sampling process, pretreatment, packaging, transfer, storage conditions and sample delivery. Carrying out the effective quality control can help to ensure the impartiality of the test results so as to provide reliable scientific basis for the department to study regulatory measures.