Agricultural branding is an important mark of agricultural modernization. Enshi Prefecture of Hubei Province is reputed as “Tobacco Kingdom” and “World Capital of Selenium”. It is also the key production area of flue-cured tobacco, burley tobacco and selenium-enriched tobacco. The tobacco industry has become a pillar industry of Enshi Prefecture. This paper firstly introduces tobacco resource and industry of Enshi Prefecture. Then, it analyzes countermeasures for tobacco branding and industrial development. Finally, it comes up with several constructive recommendations.