Regional water scarcity has motivated the South Central Texas Regional Water Planning Group to actively develop water management plans to address long-/short-term regional water needs. This study, therefore, develops an integrated Edwards Aquifer groundwater and river system simulation model to determine the "best" choice of regional water management plans using mixed-integer linear programming. The economic, hydrologic, and environmental consequences of the "best" choice of regional and other water management plans and options are evaluated and compared. Results indicate a tradeoff between the economic and environmental benefits. A slight decrease in economic benefit results in a substantial increase in environmental benefit.