Agricultural polices in the EU are increasingly targeting not only the agricultural sector but also other economic branches. The indirect effects of these policies, as the rural development ones, might be as important as the direct ones, mainly on factor markets as labour. In addition, in order to better scale the adopted agricultural measures, policy makers are devoting more attention to the regionalized impacts of these policies. For these reasons, a pure partial-equilibrium agricultural model is not enough to account the effects of the EU agricultural policies. The development of regionalized Computable General Equilibrium models and the linkages with already developed regionalized agricultural partial equilibrium models is a fundamental step for agricultural economists. The greatest challenge to build a regional general equilibrium model for all EU27 NUTS2 regions is the database construction. This work show the main steps needed to construct such a database, called IOTNUTS2.