Evaluation index system of agricultural sustainable development is constructed with the four components of social index, agricultural economic index, resources index, and environment index. According to the comprehensive evaluation model of agricultural sustainable development with the participation of single person, comprehensive evaluation model of agricultural sustainable development with the smallest generalized deviation and the participation of many people is established. Based on the case studies, agricultural sustainable development status of a certain region is evaluated. Result shows that the evaluation scores of the social index and agricultural economic index are high in this region, but the score of resources index is general and the evaluation result of environment index is not very good. The comprehensive evaluation value of overall sustainable development is 0.665 5; and the evaluation result is “good”.