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Objective: Analyze the production of polyhydroxyalkanoates (PHA) by Bacillus subtilis sp., subtilis in submerged culture using pear residues as a carbon source. Design/methodology/approach: The culture consisted of pear residue f lour concentrations of 5 and 15% for 72 h. Reducing sugars, biomass, pH, protein, and pHA extraction and quantification were analyzed during submerging cultivation of Bacillus subtilis sp., subtilis.Results: The results showed that Bacillus subtilis sp., subtilis can grow and generate PHA, having its maximum proportion in PHA extract of 0.094 g/L at 72h of culture, at a substrate concentration of 5%. Study limitations/implications: More studies related to the optimization of culture conditions for PHA production are required and prior treatment of pear waste f lour will be considered.Findings/Conclusions: The synthesis of these biopolymers is important to promote their large-scale production using agro-industrial waste, thus contributing to reduce the environmental impact.

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