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Abstract
Objective: To describe the main blood disorders caused by hypophosphatemia (low P level in the blood) in dairy cows. Design/Methodology/Approach: Publications about blood disorders caused by hypophosphatemia in dairy cows were analyzed. Results: In addition to a decrease in milk production and several reproductive and metabolic disorders, hypophosphatemia can cause alterations in blood cells, mainly in erythrocytes, as a consequence of the decrease of the phosphorus (P) needed to generate adenosine triphosphate (ATP) and the alterations of the cell membrane phospholipids. Study Limitations/Implications: Few studies have described how P affects different blood cells or their components. Findings/Conclusions: Hypophosphatemia has been associated with structural and functional alterations in blood cells.