[Objectives] To study the changes in large livestock breeding industry and their influences on gross output value of animal husbandry in Guyuan City of Ningxia. [Methods] This study explored the change trends of large livestock breeding industry and their impacts on animal husbandry income based on a linear trend method and ridge regression model. [Results] The numbers of sold and slaughtered cattle and sheep in Guyuan presented a significant upward trend, while the number for hog had a significant downward trend, during 2000-2019. The gross output value of animal husbandry (GOVAH) in Guyuan and its 5 counties had increased by 2-3 times in recent 20 years, which was mainly driven by large-scale livestock breeding. The cattle and sheep breeding sectors had positive effects on GOVAH, while the hog breeding sector had negative effect. [Conclusions] This study provides a reference for the structural adjustment and large-scale development of animal husbandry.