There were dramatic increases in cost of insect control from 1969 to 1974. The large increase in the usage of toxaphene and methyl parathion between 1972 and 1974 reflect the impact of banning DDT. A mixture of these two insecticides was the best alternative mixtures using DDT. This information was obtained from the national cotton cost surveys conducted in 1969, 1972 and 1974 and supplemented by data for various subregions of the cotton belt. Data on cost and quantities of specific major insecticides used on cotton is reported for the entire belt. Data on acres treated, cost per acre, and average number of applications per treated acre are included.