Large-scale breeding of livestock and poultry is the main way of modern animal husbandry development. This breeding method is widely used by the majority of owners because of its easy technical promotion, low breeding cost and good economic benefits. But with the development of large-scale livestock and poultry breeding, the pollution and damage to the environment caused by fecal pollution from large-scale livestock and poultry breeding has been criticized by many environmentalists.In this paper, through visit and investigation of large-scale livestock and poultry farms, the methods and measures of environmental protection in the construction of large-scale livestock and poultry farms are proposed.